Pharmaceuticals/Biotechnology(Equipment and Consumables)

Features: Flexible, reinforced vinyl chloride chambers featuring a lower price and running cost compared with conventional glove boxes; - The transparent vinyl material used ensures high visibility and operability inside the chamber.
- Capable of creating an anaerobic environment with an oxygen concentration of 5 ppm or below.
- The positive pressure maintaining chamber facilitates gas leak detection.
- Lower price and maintenance cost than with the hard-box type
- The auto air-lock model automatically creates an anaerobic state in the entry box.
- Abundant accessories available facilitate the introduction of equipment into the chamber.
- Sizes are customizable according to the application.

Applications

Culture research on anaerobic microorganisms in anoxic ecosystems (soil bacteria, ruminant animal enteric bacteria, etc.)
Animal cell apoptosis (cell death) research
Marine microbial ecology research, etc.
Anaerobic site testing in the clinical laboratory

Product Catalog (PDF: 1,043KB)

Direct-Flow Filtration for Microfiltration and Aseptic Filtration Purposes (Spectrum)

The Spectrum hollow fiber microfiltration membrane is a superior product actively used in applications such as unheated sterilization, clarifying filtration, and terminal filtration. The module incorporates intricately looped hollow fibers (DynaFibre®) made of mixed cellulose ester (ME) with 0.2-μm inner diameter. With a large surface area on a compact unit, this structure contributes to higher permeation rates and less clogging. The ME membrane is also known for its property of low protein adsorption (< 2 μg/cm2). Such high levels of efficiency are made possible only by the hollow fiber filter. Its mechanism allows fluid outside the porous hollow fiber to penetrate the outer surface into the lumen; then, such fluid streams converge and flow out from a common outlet port into a flow path. Furthermore, hydrophobic bent fibers incorporated in the microfiltration membrane (for models other than DynaGard) allow air bubbles to escape. Therefore, the structure is less likely to undergo the air lock phenomenon (in which bubbles impede the normal flow of fluid).

Tangential Flow Filtration for Microfiltration and Ultrafiltration Purposes: The disposable MicroKros hollow fiber filter module is designed for a gentle tangential flow filtration for a small sample volume from 1 to 100 mL. This module represents an efficient and practical means of tangential flow filtration for fluid volumes typically used in research and development environments. Although the MicroKros filter is normally used while connected to a peristaltic pump, it can also be manually operated when the sample volume is small. When condensing a fluid, two syringes are connected to the inlet and outlet ports on the impenetrable constituent side so that the sample fluid freely travels hollow fiber lumens. A third syringe is connected to one of the side ports to collect filtrate. By connecting a fourth syringe using the supplied check valve (blue), you can add a sample fluid for condensation or attach a buffer for diafiltration.

Main Product Lines

Spectrum deals in five types of hollow fiber microfiltration membrane modules.

- MiniKap
- MediaKap
- MediaKap Plus
- CultureGard
- Dyna-Gard

Tangential Flow Filtration (TFF) (Spectrum)

For the condensation, purification and impurity removal with biological materials and other particle solutions, common methods used are filtration and centrifugal separation. With centrifugal separation, a sequence of rotation, supernatant removal, and pellet redistribution takes several hours. It is, therefore, not uncommon for users of this method to experience the deterioration of target analytes, reduced yields, and failure to achieve high purity. The most common method of filtration employed in laboratories is direct flow filtration, but this method too is time-consuming due to clogging. In contrast, tangential flow filtration completes separation in a significantly shorter time. By using a hollow fiber TFF filter module, you can complete condensation and purification within an hour, with high levels of purity and yield.

Efficient Filtration in a Short Time

- Separation within 5 to 30 minutes
- Purity of 90 to 99%
- Dual-mode: Pump operation and manual operation
- Yield of 85 to 95%
- Gentle process

Main Applications

- Cell condensation
- Protein purification
- Cell diafiltration
- Protein condensation
- Virus purification
- Protein diafiltration
- Virus diafiltration
- Particle diafiltration
- Virus impurity removal
- Nanoparticle condensation
- Residue removal from cell lysates
- Nanoparticle diafiltration
- Bacterial condensation
- Nucleic acid condensation
- Bacterial diafiltration

Contact us about scalability for your application.

Tangential Flow Filtration (TFF) Experimental Systems (Spectrum)

Tangential Flow Filtration (TFF) Experimental Systems
(Spectrum)
The KrosFlo® Research IIi tangential flow filtration (TFF) system is ideal for microfiltration and ultrafiltration experiments at R&D scales with sample fluid volumes of 1 mL to 10 L. The fully-integrated KrosFloResearch IIi TFF system, combined with a KrosFlo hollow fiber membrane filter, offers the following advantages:

- Processing in a short time
- Maintaining a flow rate of 1 mL or less
- Outstanding membrane separation performance
- Disposable filtration flow path

Main Applications

- Cell harvest and clarifying filtration
- Separation and diafiltration of latex particles
- Cell debris removal
- Bacterial condensation and diafiltration
- Purification of virus and virus-like particles (VLPs)
- Separation and diafiltration of nanoparticles
- Protein purification
- Antibody purification
- Nucleic acid purification
- Cellular perfusion and medium replacement in a bioreactor
- Cellular perfusion and medium replacement in a bioreactor

Contact us for more details.

This new tabletop washer system employs a horizontal dehydration mode (centrifugal dehydration) to respond to washing operation for low-volume microplates, such as the 384-well and 1,536-well, especially to cope with difficulty in fluid suction and discharge involved in its operation.
Apart from the washing function, it is also possible to defoam the sample in the plate.
The system comes with a stacker that can be set with 40 microplates; the user can choose from two types of wash solutions and switch between various washer modes. For the centrifugal dehydration of microplates, a horizontal rotation mode (patent pending) can be used, with dehydration rotational frequency set optionally. Thus, the system eliminates the conventional problems of residual fluid and sample dehydration.

Product Catalog (PDF: 2,374KB)

This new tabletop washer system employs a horizontal dehydration mode (centrifugal dehydration) to respond to washing operation for low-volume microplates, such as the 384-well and 1,536-well, especially to cope with difficulty in fluid suction and discharge involved in its operation.
Apart from the washing function, it is also possible to defoam the sample in the plate.
The system comes with a stacker that can be set with 40 microplates; the user can choose from two types of wash solutions and switch between various washer modes. For the centrifugal dehydration of microplates, a horizontal rotation mode (patent pending) can be used, with dehydration rotational frequency set optionally.

Product Catalog (PDF: 2,466KB)

We offer a wide range of furnishings indispensable to biotechnology research, including medical and other types of freezers, cultivation equipment, and sterilizing/drying machines.

Panasonic Healthcare Co., Ltd.

We have a wide selection of general-purpose biotechnology equipment and consumables, including pipettes, dispenser, stirrers, chips, and plates.

Features: - Automatically seals a variety of microplates.
- High-speed processing at approx. 6 sec per plate
- Low-temperature film (MEPL5-500) enables sealing
    at approx. 110°C. Significantly reduces thermal stress
    to valuable specimens.
- Low-temperature sealing prevents microplate rims
    from collapsing, allowing microplates to be reused.